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Gastrointestinal Stromal Tumor (GIST)

A gastrointestinal stromal tumor (GIST) is a type of GI tumor. GISTs are different than other, more common types of GI tumors because of the type of tissue in which they start. Originally, GISTs were thought to be either muscle or nerve tumors, but modern research shows that GISTs start in cells found in the walls of the GI tract, called interstitial cells of Cajal (ICC). These cells send signals to the GI tract to help move food and liquid through the system.